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Zovirax (Acyclovir), also commonly known as Acyclovir, is a synthetic purine nucleoside analogue. Studies on cell cultures have proven its great anti-viral potential against such viruses as human herpes virus, varicella zoster virus, Epstein Barr virus or cytomegalovirus, against which it takes very effective in vitro and vivoinhibitory actions.
The primary use for Zovirax (Acyclovir) is to inhibit and stop the production of herpes virus, its actions limiting the effects of herpes virus outbreaks in length and severity, on mucous membranes or skin. Its usage is also recommended in treating recurring genital herpes, Shingles or herpes zoster infections. Zovirax (Acyclovir) can be prescribed for patients with severe AIDS (with CD4 count of under 50 per micro liter) or for patients that undergo operations such as allogenic bone marrow transplant.
Extra precaution is are to be taken by patients with wounds or open lesions, due to easier transmission of the infections.Although Zovirax (Acyclovir) has no known adverse effect on fertility, its use by pregnant or nursing women may be hazardous due to its tendency to pass into the breast milk. Therefore, prior consulting with your doctor is recommended in such cases. Elderly patients are strongly advised to keep proper hydration by consuming lots of liquids while under Zovirax (Acyclovir) treatment, due to the great increase in creatinine levels. Proper hydration helps keeping creatinine levels to an optimum level.Also, Zovirax (Acyclovir) may not be recommended to patients suffering from liver, kidney or brain disorders.
While following a treatment with Zovirax (Acyclovir), the patient must follow the exact instructions that the doctor has given him. Each dose of the drug should be accompanied by a glass of water. Consumption of plenty of fluids may also be advised to patients under Zovirax (Acyclovir) treatment.
The correct dosage of Zovirax (Acyclovir) should be obtained by the patient’s personal doctor, because the suitable dosage of the drug depends on several factors. It can vary from 200 mg 5 times per day (Herpex simplex infections, double dosage for patients with a greater risk of vulnerability, such as patients with recent history of bone marrow transplant), 200 mg every 6 hours (or 400 mg every 12 hours), in cases of satisfactory immunity. It is advised to interrupt Zovirax (Acyclovir) treatment at a 6-12 month interval, to examine the changes in the disease history and for monitoring the virus patterns.
In herpes zoster treatment, the recommended dosage is 800 mg Zovirax (Acyclovir) at 4 hour intervals (5 intakes in all omitting the night dosage), for an estimated duration of a week. In severe AIDS conditions, with CD4 counts of less than 50 per micro liter, as well as for patients that undergo allogenic bone marrow transplants, the Zovirax (Acyclovir) dosage will be 800 mg per intake every 6 hours.For the treatment of children of 2 or more years of age infected with Herpes Simplex, normal Zovirax (Acyclovir) dosage for adults may be prescribed.
The dosage shall be halved in cases where patients are children under 2 years of age. Normal dosage for adults is also recommended for treatment of children with AIDS with CD4 count of under 50 per micro liter.It is recommended that the Zovirax (Acyclovir) dosage should be carefully monitored for patients that are suffering from renal impairment, as the acyclovir levels can rise above the safe counts. The Zovirax (Acyclovir) dosage in such cases should never exceed two intakes per day, in 200 mg doses.
If you have taken a bigger dose of the drug than prescribed by your doctor (or if you are experiencing any abnormal or disturbing side effects) you should seek medical attention immediately, either consulting a doctor or going to the hospital.
It is recommended that the patient should not miss any of his doses of Zovirax (Acyclovir). However, if he or she happens to miss one, it should be taken in as soon as the patient remembers. If it is almost time for another dose of Zovirax (Acyclovir), it is best for the patient to skip the missed dose and to continue following his regular treatment schedule. Taking a double dose of the drug is strictly prohibited, unless the prescribing doctor advises otherwise.
If you are experiencing any of these side effects during your treatment with Zovirax (Acyclovir) you should stop taking the drug and inform you doctor as soon as possible
While the most commonly reported side effects of Zovirax (Acyclovir) treatments are allergic rashes, there are other symptoms that have been observed during Zovirax (Acyclovir) treatments, such as gastrointestinal problems (nausea, vomiting, diarrhea, abdominal pains), headaches, dizziness, fatigue, hair loss, tiredness or bruising.
Inform your doctor if you are experiencing anything unusual during your treatment.
There are no known reactions between Zovirax (Acyclovir) and other drugs, apart from Probenecid which increases the acyclovir's mean half-life.
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